Novel measurement system for respiratory aerosols and droplets in indoor environments

The SARS-CoV-2 pandemic has created a great demand for a better understanding of the spread of viruses in indoor environments. A novel measurement system consisting of one portable aerosol-emitting mannequin (emitter) and a number of portable aerosol-absorbing mannequins (recipients) was developed that can measure the spread of aerosols and droplets that potentially contain infectious viruses. The emission of the virus from a human is simulated by using tracer particles solved in water. The recipients inhale the aerosols and droplets and quantify the level of solved tracer particles in their artificial lungs simultaneously over time. The mobile system can be arranged in a large variety of spreading scenarios in indoor environments and allows for quantification of the infection probability due to airborne virus spreading. This study shows the accuracy of the new measurement system and its ability to compare aerosol reduction measures such as regular ventilation or the use of a room air purifier.     

Zika Virus Growth in Human Kidney Cells Is Restricted by an Elevated Glucose Level

Mosquito-borne Zika virus (ZIKV) became a real threat to human health due to the lack of vaccine and effective antiviral treatment. The virus has recently been responsible for a global outbreak leading to millions of infected cases. ZIKV complications were highlighted in adults with Guillain–Barré syndrome and in newborns with increasing numbers of congenital disorders ranging from mild developmental delays to fatal conditions. The ability of ZIKV to establish a long-term infection in diverse organs including the kidneys has been recently documented but the consequences of such a viral infection are still debated. Our study aimed to determine whether the efficiency of ZIKV growth in kidney cells relates to glucose concentration. Human kidney HK-2 cells were infected with different ZIKV strains in presence of normal and high glucose concentrations. Virological assays showed a decrease in viral replication without modifying entry steps (viral binding, internalization, fusion) under high glucose conditions. This decrease replication was associated with a lower virus progeny and increased cell viability when compared to ZIKV-infected HK-2 cells in normal glucose concentration. In conclusion, we showed for the first time that an elevated glucose level influences ZIKV replication level with an effect on kidney cell survival.     

Alternatives for improving energy security in Cape Verde

The lack of consensus on the meaning of energy security and how it should be measured hinders the evaluation of alternatives for improving the Cape Verdean energy sector. The objective of the paper is to develop an energy security index adjusted to the country's context. The methods used are the multi-criteria analysis and the Delphi survey. Different alternatives to improve energy security are assessed: electrically interconnect Cape Verde's islands, increase the share of renewable energy, and a combination of the previous alternatives. The results of our analysis indicate that increasing renewable energy is the optimal alternative for Cape Verde.     

Design of novel urogenital pharmabiotic formulations containing lactobacilli,salivaricin CRL 1328 and non-microbial compounds with different functionalities

Context: The administration of pharmabiotics is a promising alternative to antimicrobial drugs for the treatment and/or prevention of female urogenital infections.

Objective: To design pharmabiotic formulations including bioactive ingredients of microbial origin combined with non-microbial substances and then to evaluate the stability of the combinations during freeze-drying and storage.

Materials and methods: Different formulations including Lactobacillus gasseri CRL 1263, Lactobacillus salivarius CRL 1328, salivaricin CRL 1328 (a bacteriocin) and non-microbial compounds (lactose, inulin and ascorbic acid) were assayed, and the ingredients were freeze-dried together or separately. The formulations were stored in gelatin capsules at 4?°C for 360?d.

Results: The viability of lactobacilli was affected to different extents depending on the strains and on the formulations assayed. L. salivarius and ascorbic acid were successfully combined only after the freeze-drying process. Salivaricin activity was not detected in formulations containing L. gasseri. However, when combined with ascorbic acid, lactose, inulin or L. salivarius, the bacteriocin maintained its activity for 360?d. The selected microorganisms proved to be compatible for their inclusion in multi-strain formulations together with lactose, inulin and ascorbic acid. Salivaricin could be included only in a L. salivarius CRL 1328 single-strain formulation together with non-microbial substances.

Conclusions: This study provides new insights into the design of urogenital pharmabiotics combining beneficial lactobacilli, salivaricin CRL 1328 and compounds with different functionalities.     

马脊梁煤矿井下巷道贯通测量方法分析

在煤矿测量工作中,贯通测量是其中重要工作之一,确保贯通点的误差在设定的范围内,决定了贯通测量的成败。本文将马脊梁煤矿副立井与王村回风立井的贯通作为研究对象,选择使用井下控制测量、竖井联系测量及陀螺定向技术等,设定了贯通测量的方案,开展了误差预计,通过对比预计结果和要求,保证了贯通测量设计的可行性。     

控制理论的现状及对它的期望

本文首先简述了控制理论的发展过程，侧重叙述促进现代控制理论发展的主要因素，然后叙述了控制理论主要研究方向的进展及有待解决的问题，最后从第十二届ＩＦＡＣ世界大会看人们如何对待控制理论的各个方面。     

云南滇池湖泊流域水土流失灾害遥感调查

采用遥感技术与地面调查相结合的方法，组织多学科综合调查研究，对云南滇池流域水土流失状况及程度进行了调查分析。初步查明了引起水土流失灾害的原因并提出相应的防止对策。     

Public Attitudes to In-House Water Recycling in England and Wales

This study, which is based on responses from over 300 individuals in England and Wales, explores how a willingness to use a water-recycling system of specific configuration varies against a number of factors which are linked to system design, system scale, system context, and water-conservation behaviour. Findings show that there is broad willingness to accept in-house water recycling provided that public health is not compromised.     

关于统计调查方法改革的探讨

统计调查是统计工作的最基本环节，统计工作的质量在很大程度上取决于统计调查的质量。我国原有的统计调查方法体系已不再适应社会主义市场经济的新形势。鉴于面临着改革的新问题，论述了统计调查方法体制改革的目标模式和原则，提出了科学合理的统计调查体系，使统计工作更发适应社会主义市场经济体制的需求。     

RTK技术在控制测量中的应用研究

GPS RTK(Real Time Kinematic)技术的快速定位功能为其应用创造了良好的条件,但其定位精度验后估计的欠缺又使其应用受到一定的限制。本文针对此问题进行了研究,给出了GPS RTK测量成果的精度估计方法,并对GPS RTK测量技术用于控制测量的可行性进行了探讨,导出了相应的测量限差,为CPS RTK测量技术用于控制测量提供了理论依据和技术规定。